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Living With Myelofibrosis

Oncology

Florida Premier Research Institute

Florida Premier Research Institute, and Florida Pulmonary Research Institute are State-of-the-Art, Multi-Specialty facilities conducting Phase I-IV clinical trials in the Orlando, Florida, metropolitan area. Our Principal Investigator, Dr. Faisal A. Fakih and staff are fully committed to finding new medical treatments to improve the millions of lives affected by a… Continue reading

Dr. Hugh-Jones Discusses the JAK2 Inhibitor SAR302503

Charles Hugh-Jones, MD, Vice President, Head of Medical Oncology Affairs, Sanofi North America, discusses the results of a phase I/II study looking at SAR302503, an investigational oral JAK2-selective inhibitor for patients with myelofibrosis. The trial enrolled 59 patients; 44 with primary myelofibrosis, 12 post-polycythemia vera, and 4 post-essential thrombocythemia. 86%… Continue reading

Dr. Ruben Mesa Discusses the COMFORT Ruxolitinib Trials

Ruben A. Mesa, MD, Professor of Medicine, Chair, Division of Hematology & Medical Oncology, Mayo Clinic, Arizona, discusses the phase III Controlled Myelofibrosis Study with Oral JAK Inhibitor Treatment (COMFORT) trials, which led to the FDA approval of ruxolitinib (Jakafi) for patients with myelofibrosis. COMFORT-I was a placebo controlled studied… Continue reading

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